Methyl 4-hydroxy-2-methyl-1

Name : Methyl 4-hydroxy-2-methyl-1,1-dioxo-1,2-dihydro-1,2-benzothiazine-3-carboxylate
Synonym : 4-Hydroxy-2-methyl-1,1-dioxo-1,2-dihydro-1,2-benzothiazine-3-carboxylic acid methyl ester; Meloxicam EP Impurity E
Mol Formula : C11H11NO5S
CAS : 35511-15-0


Methyl 4-hydroxy-2-methyl-2H-1,2-benzothiazine-3-carboxylate 1,1-dioxide

CAS Number:35511-15-0
Molecular Weight:269.27
Molecular Formula:C11H11NO5S
Technical data
Physical State :Solid
Solubility :Soluble in Chloroform
Storage :Store at -20° C
Melting Point :163-165°C (lit.)

4-Hydroxy-1-methyl-2(1H)-quinolone was used as nucleophile in electrochemical oxidation of catechols and the reaction was studied by cyclic voltammetry and controlled-potential coulometry[1]. It was used in ceric ammonium nitrate-mediated oxidative cycloaddition of 1,3-dicarbonyls to conjugated compounds to yield substituted dihydrofurans, dihydrofurocoumarins, dihydrofuroquinolinones and dihydrofurophenalenones[2]. It was used in the synthesis of :
• 3-(4-methoxybenzyl)-4-hydroxy-1-methylquinolinone[3]
• 3-(benzo[d][1,3]dioxol-5-ylmethyl)-4-hydroxy-1-methylquinolin-2(1H)-one[3]
• 3-(4-chlorobenzyl)-4-hydroxy-1-methylquinolin-2(1H)-one[3]
• 3,3′-bis(4-chlorobenzylidene)-1,10-methylquinolin-2,20-(1H)-one[3]


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