Ethyl Oleate manufacturer

Properties

Melting point:
−32 °C(lit.)
Boiling point:
216-218 °C15 mm Hg
Density 
0.87 g/mL at 25 °C(lit.)
FEMA 
2450 | ETHYL OLEATE
refractive index 
n20/D 1.451(lit.)
Flash point:
>230 °F
storage temp. 
−20°C
solubility 
chloroform: soluble10%
form 
Oily Liquid
color 
Clear
Sensitive 
Light Sensitive
Merck 
14,6828
JECFA Number
345
BRN 
1727318
InChIKey
LVGKNOAMLMIIKO-VAWYXSNFSA-N

Safety Information

Safety Statements 
23-24/25-22
WGK Germany 
2
RTECS 
RG3715000
10-23
TSCA 
Yes
HS Code 
29161900
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Progress Life Sciences Pvt. Ltd. is an Ethyl Oleate manufacturer, Exporter | Supplier

 

We are an Ethyl Oleate Manufacturers, Exporters, Suppliers, Distributor, Trader and Exporters of High-Quality API, Lornoxicam, Bromhexine, Linagliptin, Sucralfate.

Our main Export in Markets, Africa, Middle East, South, Latin America, Southeast Asia, SAARC, Pakistan and Bangladesh are dealers.

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Looking for Ethyl oleate Manufacturers, Suppliers, Exporters best in India?

 

Progress Life Sciences Pvt. Ltd from India Ethyl oleate manufacturers, exporters, Suppliers best in the world.

Ethyl oleate is a fatty acid ester formed by the condensation of oleic acid and ethanol. It is a colorless oil although degraded samples can appear yellow.

Contents

Use and occurrence

Additive

Ethyl oleate is used by compounding pharmacies as a vehicle for intramuscular drug delivery, in some cases to prepare the daily doses of progesterone in support of pregnancy. Studies that document the safe use of ethyl oleate in pregnancy for both the mother and the fetus have never been performed. It is regulated as a food additive in the U.S. by the Food and Drug Administration.[2] Ethyl oleate is used as a solvent for pharmaceutical drug preparations involving lipophilic substances such as steroids.[3] It also finds use as a lubricant and a plasticizerLouis Bouveault used ethyl oleate to demonstrate Bouveault–Blanc reduction, producing oleyl alcohol and ethanol,[4] a method which was subsequently refined and published in Organic Syntheses.[5]

Ethyl Oleate manufacturer

Occurrence 

Ethyl oleate has been identified as a primer pheromone in honeybees.[6]

Precursor to other chemicals

By the process of ethenolysis, the methyl ester of oleic acid, converts to 1-decene and methyl 9-decenoate:[7]

CH
3(CH
2)
7CH=CH(CH
2)
7CO
2Me +
 CH2=CH2 → CH3(CH2)7CH=CH2 + MeO2C(CH2)7CH=CH2

Medical aspects

Ethyl oleate is produced by the body during ethanol intoxication.[8] It is one of the fatty acid ethyl esters (FAEE) produced after ingestion of ethanol. Some research literature implicates FAEEs such as ethyl oleate as the toxic mediators of ethanol in the body (pancreas, liver, heart, and brain).[9][10] Ethyl oleate may be the toxic mediator of alcohol in fetal alcohol syndrome.[9] The oral ingestion of ethyl oleate has been carefully studied and due to rapid degradation in the digestive tract it appears safe for oral ingestion.[11]

See also

 

Ethyl oleate, 99%

E 1625

Oleic acid ethyl ester, Ethyl (Z)-octadec-9-enoate

111-62-6

Grade for synthesis

CH3(CH2)7CH=CH(CH2)7COOC2H5

29161590

99%

310.51

Bottle / Drum

18%

Ethyl oleate is a fatty acid ester formed by the condensation of oleic acid and ethanol. It is a colorless to light yellow liquid. Ethyl oleate is produced by the body during ethanol intoxication.

E 1625 (OTTO) Ethyl oleate, 99% Cas 111-62-6 – used to prepare the oily phase of self-microemulsifying drug delivery system (SMEDDS) for tacrolimus (Tac).

Properties

Unsaturated fatty acids & derivatives

98%

Liquid

Clear pale yellow

-32 °C(lit.)

216-218 °C

n20/D 1.451(lit.)


Safety Information

Safety Statements 23-24/25
WGK Germany 2
RTECS RG3715000
Flash Point(F) 235.4 °F
Flash Point(C) 113 °C

Use

Ethyl oleate should be stored in a cool, dry place in a small, wellfilled, well-closed container, protected from light. When a partially filled container is used, the air should be replaced by nitrogen or another inert gas. Ethyl oleate oxidizes on exposure to air, resulting in an increase in the peroxide value. It remains clear at 5°C, but darkens in color on standing. Antioxidants are frequently used to extend the shelf life of ethyl oleate. Protection from oxidation for over 2 years has been achieved by storage in amber glass bottles with the addition of combinations of propyl gallate, butylated hydroxyanisole, butylated hydroxytoluene, and citric or ascorbic acid. A concentration of 0.03% w/v of a mixture of propyl gallate (37.5%), butylated hydroxytoluene (37.5%), and butylated hydroxyanisole (25%) was found to be the best antioxidant for ethyl oleate. Ethyl oleate may be sterilized by heating at 150°C for 1 hour.

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